Early detection of cancer in high-risk BRCA mutation carriers using liquid biopsies
Principal Investigator: Victor Velculescu | Affiliation: Johns Hopkins University
Research Keywords
Early detection
Research Questions
- What are the molecular characteristics of circulation free DNA in BRCA carriers with and without cancer?
- What is the strategy for screening?
Specific Aims
- Aim 1:
- Aim 2:
- Aim 3:
Methods
- ctDNA detection
- Sequencing